CJC-1295/Ipamorelin
CJC-1295/Ipamorelin: Growth hormone–releasing peptides that promote fat loss, muscle growth, deeper sleep, and anti-aging.
⭐⭐⭐⭐⭐Boosts Growth Hormone 5x
Potential Benefits of CJC-1295 + Ipamorelin
Physiologic GH Support
Combines a GHRH analogue (CJC-1295) with a ghrelin-receptor agonist (Ipamorelin) to encourage pulsatile growth-hormone release rather than direct GH replacement.
Sleep, Recovery & Vitality
Commonly used in programs that target deeper sleep, post-training recovery, and general vitality—paired with nutrition and training.
Body-Composition Support
When combined with diet and exercise, may assist lean-mass maintenance and fat-loss efforts.
Contraindications & Precautions
Contraindications
- Known hypersensitivity to CJC-1295, Ipamorelin, or formulation excipients
- Pregnancy or breastfeeding
- Active malignancy (or history of cancer without verified remission)
Use with Caution
- Diabetes or impaired glucose tolerance — clinician may monitor glucose/A1c
- Thyroid or pituitary disorders — specialist oversight recommended
- Cardiovascular, hepatic, or renal disease — coordinate with prescriber
- Fluid-retention symptoms (edema, carpal-tunnel-like paresthesia) — adjust or discontinue if needed
- Concurrent GH-axis therapies or weight-management drugs — avoid stacking without guidance
Results, Dosing & Side Effects
Typical Program Goals
- Support healthier sleep architecture and recovery
- Assist body-composition plans alongside diet and exercise
- Promote wellbeing/energy when clinically appropriate
- Individualized targets set by clinician and labs
Dosing & Administration
- Route: Subcutaneous injection (often evening); rotate abdomen/thigh/upper arm sites
- Schedule: Nightly or cyclical protocols per clinic; some combine both peptides in one session
- Monitoring: Clinician may track IGF-1, metabolic markers, sleep metrics, and symptoms
Exact dose and frequency are individualized. Follow your provider’s instructions.
Side Effects — Common
- Injection-site redness/itching or bruising
- Flushing, lightheadedness, headache
- Nausea, transient fatigue, vivid dreams
- Temporary water retention, joint/tunnel-like tingling
- Appetite changes (ghrelin-related with Ipamorelin)
Side Effects — Monitor/Serious
- Worsening glucose control — contact your provider
- Significant edema, palpitations, or chest pain — evaluate promptly
- Allergic reactions (rash, swelling, breathing difficulty) — seek care
Why Choose CJC-1295 + Ipamorelin?
This combo engages two complementary GH pathways: CJC-1295 (GHRH analogue) cues the pituitary to release GH in a physiologic, pulsatile manner, while Ipamorelin (ghrelin-receptor agonist) enhances that signal with minimal cortisol/prolactin overlap compared to older secretagogues.
“Within a few weeks, my sleep felt deeper and workouts recovered faster. Pairing the injections with a clean diet made the difference.” — Avery S.
Mechanism of Action
- GHRH Receptor Agonism (CJC-1295): Stimulates pituitary GH release; encourages downstream IGF-1 in a physiologic pattern
- Ghrelin Receptor Agonism (Ipamorelin): Amplifies GH pulses with selective pituitary action
- Pulsatility: Seeks to preserve natural GH rhythm vs. flat replacement
- Program Fit: Best used with sleep hygiene, resistance training, protein-forward nutrition, and clinician monitoring
Educational content only. Peptide programs should be supervised by a licensed healthcare professional and individualized to the patient.