Semax/Selank
Semax & Selank: Neuropeptides that enhance focus, reduce anxiety, and support cognitive performance.
⭐⭐⭐⭐⭐Focus + Calm Peptides
Potential Benefits of Semax / Selank
Focus & Cognitive Clarity (Semax)
Commonly used in clinics to support attention, working memory, and task switching without typical stimulant jitter.
Calm & Stress Modulation (Selank)
Reported to promote a settled, non-sedating calm for daytime use; often paired with breathwork/sleep hygiene.
Daytime-Friendly, Non-Hormonal
Intranasal peptides with quick onset, designed to complement coaching on lifestyle, sleep, and nutrition.
Important: Semax and Selank are investigational in the U.S. and not FDA-approved for any indication.
Use only under the supervision of a licensed clinician. This content is educational and not medical advice.
Contraindications & Precautions
Contraindications
- Known hypersensitivity to Semax/Selank or formulation excipients
- Pregnancy or breastfeeding (insufficient safety data)
- Active nasal/sinus infection or recent nasal surgery without clinician clearance
Use with Caution
- Seizure disorders, bipolar spectrum, or uncontrolled anxiety—specialist oversight
- Hypertension sensitive to stimulants (monitor BP/HR at start)
- Frequent nosebleeds, severe allergic rhinitis, or significant septal deviation
- Concurrent psychoactive meds (e.g., MAO inhibitors, sedatives)—coordinate with prescriber
- Using other intranasal agents (decongestants, steroids): separate dosing windows
Outcomes, Dosing & Side Effects
What Patients Commonly Report
- Semax: Crisper focus, mental stamina, easier “task switching”
- Selank: Calmer baseline, fewer stress spikes, steadier mood
- Onset typically 15–60 minutes; duration a few hours (varies by individual)
- Best outcomes with sleep, hydration, protein-forward nutrition, and stress skills
Dosing & Administration (Clinic-Directed)
- Route: Intranasal spray/drops per clinic protocol
- Frequency: Often 1–3× daily or as-needed on work/study days; cycles may be used
- Technique: Prime device → chin slightly tucked → aim laterally → gentle sniff; avoid forceful inhalation
- Spacing: If using both, separate by 5–10 minutes; avoid blowing nose for ~10–15 minutes after
- Storage: Follow label; many preparations prefer refrigeration and protection from light
Exact concentration and schedule are individualized by your licensed provider.
Side Effects — Common
- Nasal irritation/dryness, drip taste, mild headache
- Transient drowsiness (more with Selank) or alertness (more with Semax)
- Occasional vivid dreams or appetite changes
Side Effects — Serious/Rare
- Persistent anxiety, agitation, or mood changes — contact your provider
- Recurrent nosebleeds or severe nasal pain/ulceration — stop and evaluate
- Allergic reactions (rash, swelling, breathing difficulty) — seek care
Why Choose Semax / Selank?
This combo pairs complementary neuropeptides for clear-minded focus (Semax) and calm balance (Selank) with a quick, intranasal route that fits busy days—ideal alongside coaching on sleep, stress, and routines.
Patient Story:
“Semax helped me lock in for deep work; Selank kept me steady during stressful meetings. Using both with better sleep hygiene made the effect feel natural.” — Maya T.
“Semax helped me lock in for deep work; Selank kept me steady during stressful meetings. Using both with better sleep hygiene made the effect feel natural.” — Maya T.
Mechanism of Action (Proposed)
- Semax: Analog of ACTH(4–10); linked in studies to neurotrophic signaling (e.g., BDNF pathways) and attention networks
- Selank: Analog of tuftsin; associated with modulation of GABAergic tone and stress-response pathways
- Intranasal Delivery: Targets nasal mucosa for rapid onset; avoid immediate co-administration with other sprays
- Program Fit: Non-hormonal, non-stimulant approach within a comprehensive lifestyle plan
Educational content only. Semax/Selank are investigational and not FDA-approved. Any use should be individualized and overseen by a licensed medical professional.